Neuropsychological Comparison of Patients With Alzheimer's Disease and Dementia With Lewy Bodies.

ABSTRACT:

Background and purpose

This study aimed to determine the neuropsychological differences between patients with early-stage Alzheimer's disease (AD) and dementia with Lewy bodies (DLB) with a Clinical Dementia Rating (CDR) score of ≤1.

Methods

We examined 168 patients with AD (126 with CDR score=0.5, 42 with CDR score=1) and 169 patients with DLB (104 with CDR score=0.5, 65 with CDR score=1) whose diagnoses were supported by ¹⁸F-flobetaben positron-emission tomography (PET) and ¹⁸F-N-(3-fluoropropyl)-2β-carbon ethoxy-3β-(4-iodophenyl) nortropane PET. Neuropsychological test scores were compared after controlling for age, sex, and education duration. Using a cutoff motor score on the Unified Parkinson's Disease Rating Scale of 20, patients with AD were fur

SUBMITTER: Kang S 

PROVIDER: S-EPMC10622731 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature