The role of chicken eggs in modulating sarcopenic obesity and gut microbiota in db/db mice.

ABSTRACT:

Background

Sarcopenia obesity, in which loss of muscle mass and fat accumulation occur simultaneously, is the pathological basis of type 2 diabetes mellitus. The usefulness of chicken eggs in sarcopenia prevention has been reported in several previous studies. The purpose of this study was to determine the beneficial effects of chicken eggs in the prevention of sarcopenic obesity in db/db mice.

Methods

We raised 8-week-old db/db male mice, a model of sarcopenia obesity, for 8 weeks and fed them a diet mixed with dried whole eggs. The fecal microbiota transplant (FMT) group was treated with antibiotics for 2 weeks, starting at 6 weeks of age, followed by FMT twice a week until 16 weeks of age.

Results

Eggs administered to db/db mice showed increase

SUBMITTER: Okamura T 

PROVIDER: S-EPMC10622760 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature