Posttraumatic Stress Disorder Symptoms and Cardiovascular and Brain Health in Women.

ABSTRACT:

Importance

Posttraumatic stress disorder (PTSD), cardiovascular disease (CVD), and Alzheimer disease are major public health issues, particularly for women. The implications of PTSD for cardiovascular and brain health for women is poorly understood.

Objective

To assess whether PTSD symptoms among midlife women are associated with carotid intima media thickness (IMT), an indicator of carotid atherosclerosis; brain white matter hyperintensity volume (WMHV), an indicator of brain small vessel disease; and cognitive performance and to test a modifying role of the APOEε4 genotype.

Design, setting, and participants

In this cross-sectional study, participants were enrolled between 2016 to 2021 and completed questionnaires (PTSD Checklist-Civilian Version), physical measures,

SUBMITTER: Thurston RC 

PROVIDER: S-EPMC10623197 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature