TCM syndrome differentiation in colorectal cancer patients assisted by differences in gut microbiota: An exploratory study.

ABSTRACT:

Objective

To explore the difference in gut microbiota between different traditional Chinese Medicine (TCM) syndromes in patients with colorectal cancer (CRC) and its internal relationship.

Methods

From June 2020 to August 2021, 109 colorectal cancer patients with a clear pathological diagnosis who had not yet undergone surgery or chemotherapy were classified according to the TCM syndrome classification, and the feces samples of 109 patients with preoperative colorectal cancer were collected. 16s rRNA gene sequencing was used to determine gut microbiota diversity and abundance in CRC patients with different TCM syndrome, and LEfSe analysis was made to screen different TCM syndrome for differential representative microbiota.

Results

109 patients were divided into 5 synd

SUBMITTER: Ming-Bin G 

PROVIDER: S-EPMC10623286 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature