Enhancing Robustness of Adhesive Hydrogels through PEG-NHS Incorporation.

ABSTRACT: Tissue wounds are a significant challenge for the healthcare system, affecting millions globally. Current methods like suturing and stapling have limitations as they inadequately cover the wound, fail to prevent fluid leakage, and increase the risk of infection. Effective solutions for diverse wound conditions are still lacking. Adhesive hydrogels, on the other hand, can be a potential alternative for wound care. They offer benefits such as firm sealing without leakage, easy and rapid application, and the provision of mechanical support and flexibility. However, the in vivo durability of hydrogels is often compromised by excessive swelling and unforeseen degradation, which limits their widespread use. In this study, we addressed the durability issues of the adhesive hydrogels by inc

SUBMITTER: Uslu E 

PROVIDER: S-EPMC10623379 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature