Nlive: an R package to facilitate the application of the sigmoidal and random changepoint mixed models.

ABSTRACT:

Background

The use of mixed effect models with a specific functional form such as the Sigmoidal Mixed Model and the Piecewise Mixed Model (or Changepoint Mixed Model) with abrupt or smooth random change allows the interpretation of the defined parameters to understand longitudinal trajectories. Currently, there are no interface R packages that can easily fit the Sigmoidal Mixed Model allowing the inclusion of covariates or incorporating recent developments to fit the Piecewise Mixed Model with random change.

Results

To facilitate the modeling of the Sigmoidal Mixed Model, and Piecewise Mixed Model with abrupt or smooth random change, we have created an R package called nlive. All needed pieces such as functions, covariance matrices, and initials generation were programmed. T

SUBMITTER: Capuano AW 

PROVIDER: S-EPMC10623729 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature