Associations of ultra-processed food consumption, circulating protein biomarkers, and risk of cardiovascular disease.

ABSTRACT:

Background

We aim to examine the association between ultra-processed foods (UPF) consumption and cardiovascular disease (CVD) risk and to identify plasma proteins associated with UPF.

Methods

This prospective cohort study included 26,369 participants from the Swedish Malmö Diet and Cancer Study, established in 1991-1996. Dietary intake was assessed using a modified diet history method, and UPF consumption was estimated using the NOVA classification system. A total of 88 selected CVD-related proteins were measured among 4475 subjects. Incident CVD (coronary heart disease and ischemic stroke) was defined as a hospital admission or death through registers. Cox proportional hazards regression models were performed to analyze the associations of UPF intake with risks of CVD. Line

SUBMITTER: Li H 

PROVIDER: S-EPMC10623817 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature