Holo-omics analysis reveals the influence of gut microbiota on obesity indicators in Jinhua pigs.

ABSTRACT:

Background

The mechanisms behind obesity are complex and multi-faceted, involving the interplay of both host genomics and gut microbiome. In recent years, research has largely focused on these factors separately, but rarely from the viewpoint of holo-omics, which considers the host and microbiome as an integrated entity. To address this gap in knowledge, the present study aimed to investigate the holo-omics basis of obesity in Jinhua pigs, a Chinese indigenous breed known for its high degree of fat deposition and superior meat quality.

Methods

Six pigs with extreme obesity phenotype were selected from a larger cohort of eighteen Jinhua pigs, and the contents of the jejunum, cecum, and colon regions were collected after slaughter at 240 days of age. The data obtained was proc

SUBMITTER: Liu S 

PROVIDER: S-EPMC10623862 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature