Coagulation profile of neonates with hyperbilirubinaemia in full-term newborns.

ABSTRACT:

Objective

To determine the relationship between coagulation system markers and hyperbilirubinaemia in full-term neonates.

Methods

This retrospective case-control study enrolled full-term neonates with hyperbilirubinaemia and healthy control full-term neonates. Prothrombin time (PT), thrombin time (TT), fibrinogen (Fbg), activated partial thromboplastin time (APTT) and international normalized ratio (INR) were recorded. The correlation between INR and total bilirubin and between INR and indirect bilirubin was analysed by linear regression analysis. Receiver operating characteristic curve analysis was used to assess the efficacy of INR to identify neonates with hyperbilirubinaemia.

Results

This study enrolled 40 full-term neonates with hyperbilirubinaemia and 30 healthy

SUBMITTER: Zhou F 

PROVIDER: S-EPMC10623989 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature