Early surgery versus conservative treatment in patients with traumatic intracerebral hematoma: a CENTER-TBI study.

ABSTRACT:

Purpose

Evidence regarding the effect of surgery in traumatic intracerebral hematoma (t-ICH) is limited and relies on the STITCH(Trauma) trial. This study is aimed at comparing the effectiveness of early surgery to conservative treatment in patients with a t-ICH.

Methods

In a prospective cohort, we included patients with a large t-ICH (< 48 h of injury). Primary outcome was the Glasgow Outcome Scale Extended (GOSE) at 6 months, analyzed with multivariable proportional odds logistic regression. Subgroups included injury severity and isolated vs. non-isolated t-ICH.

Results

A total of 367 patients with a large t-ICH were included, of whom 160 received early surgery and 207 received conservative treatment. Patients receiving early surgery were younger (median age 54 vs.

SUBMITTER: van Erp IAM 

PROVIDER: S-EPMC10624744 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature