Digital Marker for Early Screening of Mild Cognitive Impairment Through Hand and Eye Movement Analysis in Virtual Reality Using Machine Learning: First Validation Study.

ABSTRACT:

Background

With the global rise in Alzheimer disease (AD), early screening for mild cognitive impairment (MCI), which is a preclinical stage of AD, is of paramount importance. Although biomarkers such as cerebrospinal fluid amyloid level and magnetic resonance imaging have been studied, they have limitations, such as high cost and invasiveness. Digital markers to assess cognitive impairment by analyzing behavioral data collected from digital devices in daily life can be a new alternative. In this context, we developed a "virtual kiosk test" for early screening of MCI by analyzing behavioral data collected when using a kiosk in a virtual environment.

Objective

We aimed to investigate key behavioral features collected from a virtual kiosk test that could distinguish patients w

SUBMITTER: Kim SY 

PROVIDER: S-EPMC10625097 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature