High resolution 0.5mm isotropic T₁-weighted and diffusion tensor templates of the brain of non-demented older adults in a common space for the MIITRA atlas.

ABSTRACT: High quality, high resolution T₁-weighted (T₁w) and diffusion tensor imaging (DTI) brain templates located in a common space can enhance the sensitivity and precision of template-based neuroimaging studies. However, such multimodal templates have not been constructed for the older adult brain. The purpose of this work which is part of the MIITRA atlas project was twofold: (A) to develop 0.5 mm isotropic resolution T₁w and DTI templates that are representative of the brain of non-demented older adults and are located in the same space, using advanced multimodal template construction techniques and principles of super resolution on data from a large, diverse, community cohort of 400 non-demented older adults, and (B) to systematically compare the new template

SUBMITTER: Wu Y 

PROVIDER: S-EPMC10625170 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature