Genomic potential and physiological characteristics of C1 metabolism in novel acetogenic bacteria.

ABSTRACT: Acetogenic bacteria can utilize C1 compounds, such as carbon monoxide (CO), formate, and methanol, via the Wood-Ljungdahl pathway (WLP) to produce biofuels and biochemicals. Two novel acetogenic bacteria of the family Eubacteriaceae ES2 and ES3 were isolated from Eulsukdo, a delta island in South Korea. We conducted whole genome sequencing of the ES strains and comparative genome analysis on the core clusters of WLP with Acetobacterium woodii DSM1030^T and Eubacterium limosum ATCC8486^T. The methyl-branch cluster included a formate transporter and duplicates or triplicates copies of the fhs gene, which encodes formyl-tetrahydrofolate synthetase. The formate dehydrogenase cluster did not include the hydrogenase gene, which might be replaced by

SUBMITTER: Yu J 

PROVIDER: S-EPMC10625859 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature