Association of cardiometabolic multimorbidity with motoric cognitive risk syndrome in older adults.

ABSTRACT:

Introduction

Motoric cognitive risk syndrome (MCR) is a predementia syndrome that is characterized by cognitive complaints and slow gait. Cardiometabolic multimorbidity (CMM) is associated with an increased risk of dementia. However, the relationship between CMM and MCR is still unclear.

Methods

We included 4744 participants (aged 65+ years) without MCR at baseline from the National Health and Aging Trends Study (NHATS), who were followed-up from 2011 to 2018. CMM was defined as the presence of two or more cardiometabolic diseases (including diabetes mellitus, heart disease, and stroke).

Results

CMM was significantly associated with an increased risk of MCR (hazard ratio [HR] 1.41, 95% confidence interval [CI] 1.13-1.75) in fully adjusted models. Consistent results we

SUBMITTER: Zhang H 

PROVIDER: S-EPMC10626031 | biostudies-literature | 2023 Oct-Dec

REPOSITORIES: biostudies-literature