Experiences of reduction and discontinuation of antipsychotics: a qualitative investigation within the RADAR trial.

ABSTRACT:

Background

Antipsychotics are a core treatment for psychosis, but the evidence for gradual dose reductions guided by clinicians is under-developed. The RADAR randomised controlled trial (RCT) compared antipsychotic reduction and possible discontinuation with maintenance treatment for people with recurrent psychotic disorders. The current study explored participants' experiences of antipsychotic reduction or discontinuation within this trial.

Methods

This qualitative study was embedded within the RADAR RCT (April 2017-March 2022) that recruited 253 participants from specialist community mental health services in 19 public healthcare localities in England. Participants were adults with recurrent non affective psychosis who were taking antipsychotic medication. Semi-structured

SUBMITTER: Morant N 

PROVIDER: S-EPMC10626156 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature