Clinical outcomes of automatic algorithms in cardiac resynchronization therapy: Systematic review and meta-analysis.

ABSTRACT:

Background

Algorithms to automatically adjust atrioventricular (AV) and interventricular (VV) intervals in cardiac resynchronization therapy (CRT) devices are common, but their clinical efficacy is unknown.

Objective

The purpose of this study was to evaluate automatic CRT algorithms in patients with heart failure for the reduction of mortality, heart failure hospitalizations, and clinical improvement.

Methods

We performed a systematic review and meta-analysis of randomized controlled trials (RCTs) in patients with CRT using automatic algorithms that change AV and VV intervals dynamically without manual input, on a beat-to-beat basis. We performed a subgroup analysis including intracardiac electrogram-based (EGM) algorithms and contractility-based algorithms.

Result

SUBMITTER: Knijnik L 

PROVIDER: S-EPMC10626183 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature