Bacterial quorum sensing orchestrates longitudinal interactions to shape microbiota assembly.

ABSTRACT:

Background

The mechanism of microbiota assembly is one of the main problems in microbiome research, which is also the primary theoretical basis for precise manipulation of microbial communities. Bacterial quorum sensing (QS), as the most common means for bacteria to exchange information and interactions, is characterized by universality, specificity, and regulatory power, which therefore may influence the assembly processes of human microbiota. However, the regulating role of QS in microbiota assembly is rarely reported. In this study, we developed an optimized in vitro oral biofilm microbiota assembling (OBMA) model to simulate the time-series assembly of oral biofilm microbiota (OBM), by which to excavate the QS network and its regulating power in the process.

Results

By u

SUBMITTER: Su Y 

PROVIDER: S-EPMC10626739 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature