The chromatin landscape of the euryarchaeon Haloferax volcanii.

ABSTRACT:

Background

Archaea, together with Bacteria, represent the two main divisions of life on Earth, with many of the defining characteristics of the more complex eukaryotes tracing their origin to evolutionary innovations first made in their archaeal ancestors. One of the most notable such features is nucleosomal chromatin, although archaeal histones and chromatin differ significantly from those of eukaryotes, not all archaea possess histones and it is not clear if histones are a main packaging component for all that do. Despite increased interest in archaeal chromatin in recent years, its properties have been little studied using genomic tools.

Results

Here, we adapt the ATAC-seq assay to archaea and use it to map the accessible landscape of the genome of the euryarchaeote Halof

SUBMITTER: Marinov GK 

PROVIDER: S-EPMC10626798 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature