Protection from infection and reinfection due to the Omicron BA.1 variant in care homes.

ABSTRACT:

Introduction

Following the emergence of SARS-CoV-2 in 2020, care homes were disproportionately impacted by high mortality and morbidity of vulnerable elderly residents. Non-pharmaceutical interventions (NPIs) and improved infection control measures together with vaccination campaigns have since improved outcomes of infection. We studied the utility of past infection status, recent vaccination and anti-S antibody titres as possible correlates of protection against a newly emergent Omicron variant infection.

Methods

Prospective longitudinal surveillance of nine sentinel London care homes from April 2020 onwards found that all experienced COVID-19 outbreaks due to Omicron (BA.1) during December 2021 and January 2022, despite extensive prior SARS-CoV-2 exposure and high COVID-19

SUBMITTER: Choudhry S 

PROVIDER: S-EPMC10627010 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature