Radiomics-based ultrasound models for thyroid nodule differentiation in Hashimoto's thyroiditis.

ABSTRACT:

Background

Previous models for differentiating benign and malignant thyroid nodules(TN) have predominantly focused on the characteristics of the nodules themselves, without considering the specific features of the thyroid gland(TG) in patients with Hashimoto's thyroiditis(HT). In this study, we analyzed the clinical and ultrasound radiomics(USR) features of TN in patients with HT and constructed a model for differentiating benign and malignant nodules specifically in this population.

Methods

We retrospectively collected clinical and ultrasound data from 227 patients with TN and concomitant HT(161 for training, 66 for testing). Two experienced sonographers delineated the TG and TN regions, and USR features were extracted using Python. Lasso regression and logistic analysis we

SUBMITTER: Fang M 

PROVIDER: S-EPMC10627229 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature