Autoimmune polyglandular syndrome type 4: experience from a single reference center.

ABSTRACT:

Purpose

To characterize patients with APS type 4 among those affected by APS diagnosed and monitored at our local Reference Center for Autoimmune Polyglandular Syndromes.

Methods

Monocentric observational retrospective study enrolling patients affected by APS diagnosed and monitored in a Reference Center. Clinical records were retrieved and analyzed.

Results

111 subjects (51 males) were affected by APS type 4, mean age at the onset was 23.1 ± 15.1 years. In 15 patients the diagnosis of APS was performed during the first clinical evaluation, in the other 96 after a latency of 11 years (range 1-46). The most frequent diseases were type I diabetes mellitus and celiac disease, equally distributed among sexes.

Conclusions

The prevalence of APS type 4 is 9:100,000 pe

SUBMITTER: Gatta E 

PROVIDER: S-EPMC10627240 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature