Extracellular matrix deformations of the porcine recurrent laryngeal nerve in response to hydrostatic pressure.

ABSTRACT: Damage to the recurrent laryngeal nerve (RLN) caused by supraphysiological compression or tension imposed by adjacent tissue structures, such as the aorta, may contribute to onset of idiopathic unilateral vocal fold paralysis (iUVP) resulting in difficulty speaking, breathing, and swallowing. We previously demonstrated in adolescent pigs that the right RLN epineurium exhibits uniform composition of adipose tissue, with larger quantities along its length within the neck region in contrast to the left RLN that shows greater collagen composition in the thoracic region and greater quantities of adipose tissue in the neck region. In contrast, the epineurium in piglets was primarily composed of collagen tissue that remained uniform along the length of the left and right RLNs. Tensile testing of

SUBMITTER: Kollech HG 

PROVIDER: S-EPMC10627241 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature