Expanded utility of the R package, qgg, with applications within genomic medicine.

ABSTRACT:

Summary

Here, we present an expanded utility of the R package qgg for genetic analyses of complex traits and diseases. One of the major updates of the package is, that it now includes Bayesian linear regression modeling procedures, which provide a unified framework for mapping of genetic variants, estimation of heritability and genomic prediction from either individual level data or from genome-wide association study summary data. With this release, the qgg package now provides a wealth of the commonly used methods in analysis of complex traits and diseases, without the need to switch between software and data formats.

Availability and implementation

The methodologies are implemented in the publicly available R software package, qgg, using fast and memory efficient algorithm

SUBMITTER: Rohde PD 

PROVIDER: S-EPMC10627350 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature