Predictors of outcome in the ISCHEMIA-CKD trial: Anatomy versus ischemia.

ABSTRACT:

Background

The ISCHEMIA-CKD (International Study of Comparative Health Effectiveness with Medical and Invasive Approaches-Chronic Kidney Disease) trial found no advantage to an invasive strategy compared to conservative management in reducing all-cause death or myocardial infarction (D/MI). However, the prognostic influence of angiographic coronary artery disease (CAD) burden and ischemia severity remains unknown in this population. We compared the relative impact of CAD extent and severity of myocardial ischemia on D/MI in patients with advanced chronic kidney disease (CKD).

Methods

Participants randomized to invasive management with available data on coronary angiography and stress testing were included. Extent of CAD was defined by the number of major epicardial vessels w

SUBMITTER: Bainey KR 

PROVIDER: S-EPMC10627379 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature