Remote Ischemic Conditioning for Motor Recovery after Acute Ischemic Stroke.

ABSTRACT:

Background

Remote ischemic conditioning (RIC) has shown an impressive neuroprotective effect on acute ischemic stroke (AIS) in animal experiments. But whether chronic RIC improves long-term functional outcomes remains unclear.

Materials and methods

We performed a non-randomized controlled trial. Eligible patients (aged 18 -80 y) with hemiplegia caused by AIS were allocated to the RIC group and the control group. All participants received normal protocol rehabilitation therapy. Patients in the RIC group underwent RIC twice daily for 90 days. The outcome included the 90-day Fugl-Meyer Assessment (FMA) scores and modified Rankin's scale (mRS) scores, as well as changes in angiogenesis-related factors in serum from baseline to 90 days.

Results

Twenty-seven patients were i

SUBMITTER: Yu W 

PROVIDER: S-EPMC10627541 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature