Epidemiologic characteristics and a prognostic nomogram for patients with vulvar cancer: results from the Surveillance, Epidemiology, and End Results (SEER) program in the United States, 1975 to 2016.

ABSTRACT:

Objective

To elucidate clinical characteristics and build a prognostic nomogram for patients with vulvar cancer.

Methods

The study population was drawn from the Surveillance, Epidemiology, and End Results (SEER) database. Patients were randomly assigned to training and validation sets. Cox proportional hazards model and competing risk model were used to identify the prognostic parameters of overall survival (OS) and cancer-specific survival (CSS) to construct a nomogram. The nomogram was assessed by concordance index (C-index), area under the curve (AUC), calibration plot, and decision curve analysis (DCA).

Results

A total of 20,716 patients were included in epidemiological analysis, of whom 7,025 patients were selected in survival analysis, including 4,215 and 2,810

SUBMITTER: Wei S 

PROVIDER: S-EPMC10627757 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature