Continuous glucose monitoring-derived time in range and CV are associated with altered tissue characteristics of the carotid artery wall in people with type 2 diabetes.

ABSTRACT:

Aims/hypothesis

Previous studies have suggested that glucose variability may accelerate atherosclerosis progression in people with type 2 diabetes. Current guidelines recommend assessing glycaemic control using continuous glucose monitoring (CGM), which provides a comprehensive glycaemic profile to supplement HbA_1c measurement. However, the association between CGM-derived metrics and atherosclerosis progression is not entirely clear.

Methods

This exploratory study used baseline data and data obtained after 104 weeks from an ongoing prospective, multicentre, observational study. Six hundred study participants with type 2 diabetes and no apparent history of symptomatic cardiovascular disease underwent CGM and ultrasonographic atherosclerosis measurements of the caro

SUBMITTER: Mita T 

PROVIDER: S-EPMC10627957 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature