Hippocampal volume mediates the relationship of parental rejection in childhood with social cognition in healthy adults.

ABSTRACT: Childhood abuse reduces hippocampal and amygdala volumes and impairs social cognition, including the ability to recognize facial expressions. However, these associations have been studied primarily in individuals with a history of severe abuse and psychiatric symptoms; researchers have not determined whether these associations can also be observed in healthy adults. In the present study, we analyzed data from 400 healthy adults (208 men and 192 women) at Tamagawa University. Parental rejection reflecting childhood abuse was assessed using the short form of Egna Minnen Beträffande Uppfostran, while social cognition was assessed using the "Fake Smile Detection Task." Hippocampal and amygdala volumes were extracted from T1-weighted magnetic resonance imaging data using FreeSurfer. We found th

SUBMITTER: Kawamoto M 

PROVIDER: S-EPMC10628272 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature