End to end stroke triage using cerebrovascular morphology and machine learning.

ABSTRACT:

Background

Rapid and accurate triage of acute ischemic stroke (AIS) is essential for early revascularization and improved patient outcomes. Response to acute reperfusion therapies varies significantly based on patient-specific cerebrovascular anatomy that governs cerebral blood flow. We present an end-to-end machine learning approach for automatic stroke triage.

Methods

Employing a validated convolutional neural network (CNN) segmentation model for image processing, we extract each patient's cerebrovasculature and its morphological features from baseline non-invasive angiography scans. These features are used to detect occlusion's presence and the site automatically, and for the first time, to estimate collateral circulation without manual intervention. We then use the extra

SUBMITTER: Deshpande A 

PROVIDER: S-EPMC10628321 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature