Two cases of metformin-associated lactic acidosis in post-operative period in emergency department: time to be aware-case reports.

ABSTRACT:

Background

Diabetic patients on metformin therapy may be vulnerable to lactic acidosis during acute illness. This is particularly true since the comorbid conditions among patients with diabetes and the frequent use of renin-angiotensin system blockers increase the risk of renal dysfunction.

Case description

We present two cases of metformin-associated lactic acidosis (MALA) occurred after abdominal surgery. A 74-year-old woman presented to emergency department (ED) for a transient loss of consciousness. She had vomiting, diarrhea, and lack of appetite in the last 3 days and she had had an abdominal adhesiolysis surgery 12 days before. A 78-year-old man, with history of right hemicolectomy performed 15 days before admission to ED. Patient presented with diffuse abdominal pain

SUBMITTER: Angeletti C 

PROVIDER: S-EPMC10628396 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature