Fluid loading during the hemodynamic evaluation of pulmonary hypertension: a cross-sectional study.

ABSTRACT:

Background

Compensated pulmonary hypertension due to left heart disease (PH-LHD) may be difficult to identify based on resting hemodynamics. Fluid challenge is commonly used to unmask occult PH-LHD. We sought to determine the hemodynamic effect of fluid loading and its association with the clinical pretest probability of PH-LHD.

Methods

We included consecutive patients evaluated for PH who underwent right heart catheterization (RHC) with fluid challenge at Cleveland Clinic between April 2013 and January 2019. We obtained hemodynamic measurements at rest and after intravenous rapid fluid challenge (500 mL of normal saline). We calculated the pretest probability of PH-LHD based on the 6^th World Symposium on PH proceedings. For statistical analyses we used t-t

SUBMITTER: Qaiser KN 

PROVIDER: S-EPMC10628419 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature