Endometrial scratching in women undergoing IVF/ICSI: an individual participant data meta-analysis.

ABSTRACT:

Background

In IVF/ICSI treatment, the process of embryo implantation is the success rate-limiting step. Endometrial scratching has been suggested to improve this process, but it is unclear if this procedure increases the chance of implantation and live birth (LB) and, if so, for whom, and how the scratch should be performed.

Objective and rationale

This individual participant data meta-analysis (IPD-MA) aims to answer the question of whether endometrial scratching in women undergoing IVF/ICSI influences the chance of a LB, and whether this effect is different in specific subgroups of women. After its incidental discovery in 2000, endometrial scratching has been suggested to improve embryo implantation. Numerous randomized controlled trials (RCTs) have been conducted, showing

SUBMITTER: van Hoogenhuijze NE 

PROVIDER: S-EPMC10628489 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature