Endometrial receptivity in women of advanced age: an underrated factor in infertility.

ABSTRACT:

Background

Modern lifestyle has led to an increase in the age at conception. Advanced age is one of the critical risk factors for female-related infertility. It is well known that maternal age positively correlates with the deterioration of oocyte quality and chromosomal abnormalities in oocytes and embryos. The effect of age on endometrial function may be an equally important factor influencing implantation rate, pregnancy rate, and overall female fertility. However, there are only a few published studies on this topic, suggesting that this area has been under-explored. Improving our knowledge of endometrial aging from the biological (cellular, molecular, histological) and clinical perspectives would broaden our understanding of the risks of age-related female infertility.

Obje

SUBMITTER: Pathare ADS 

PROVIDER: S-EPMC10628506 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature