Alterations in faecal microbiome and resistome in Chinese international travellers: a metagenomic analysis.

ABSTRACT:

Background

International travel increases the risk of acquisition of antibiotic-resistant bacteria and antibiotic resistance genes (ARGs). Previous studies have characterized the changes in the gut microbiome and resistome of Western travellers; however, information on non-Western populations and the effects of travel-related risk factors on the gut microbiome and resistome remains limited.

Methods

We conducted a prospective observational study on a cohort of 90 healthy Chinese adult residents of Hong Kong. We characterized the microbiome and resistome in stools collected from the subjects before and after travelling to diverse international locations using shotgun metagenomic sequencing and examined their associations with travel-related variables.

Results

Our result

SUBMITTER: Cheung MK 

PROVIDER: S-EPMC10628765 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature