Circulating tumor biomarkers in early-stage breast cancer: characteristics, detection, and clinical developments.

ABSTRACT: Breast cancer is the most common form of cancer in women, contributing to high rates of morbidity and mortality owing to the ability of these tumors to metastasize via the vascular system even in the early stages of progression. While ultrasonography and mammography have enabled the more reliable detection of early-stage breast cancer, these approaches entail high rates of false positive and false negative results Mammograms also expose patients to radiation, raising clinical concerns. As such, there is substantial interest in the development of more accurate and efficacious approaches to diagnosing breast cancer in its early stages when patients are more likely to benefit from curative treatment efforts. Blood-based biomarkers derived from the tumor microenvironment (TME) have frequently

SUBMITTER: Qiu J 

PROVIDER: S-EPMC10628786 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature