A polyoxomolybdate-based hybrid nano capsule as an antineoplastic agent.

ABSTRACT: Polyoxometalates (POMs) are versatile anionic clusters which have attracted a lot of attention in biomedical investigations. To counteract the increasing resistance effect of cancer cells and the high toxicity of chemotherapeutic treatments, POM-based metallodrugs can be strategically synthesized by adjusting the stereochemical and physicochemical features of POMs. In the present report a polyoxomolybdate (POMo) based organic-inorganic hybrid solid (C₆H₁₆N)(C₆H₁₅N)₂[Mo₈O₂₆]·3H₂O, solid 1, has been synthesized and its antitumoral activities have been investigated against three cancer cell lines namely, A549 (Lung cancer), HepG2 (Liver cancer), and MCF-7 (Breast cancer) with IC50 values 56.2 μmol L^-1

SUBMITTER: Joshi A 

PROVIDER: S-EPMC10628982 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature