Impact of xylose epimerase on sugar assimilation and sensing in recombinant Saccharomyces cerevisiae carrying different xylose-utilization pathways.

ABSTRACT:

Background

Over the last decades, many strategies to procure and improve xylose consumption in Saccharomyces cerevisiae have been reported. This includes the introduction of efficient xylose-assimilating enzymes, the improvement of xylose transport, or the alteration of the sugar signaling response. However, different strain backgrounds are often used, making it difficult to determine if the findings are transferrable both to other xylose-consuming strains and to other xylose-assimilation pathways. For example, the influence of anomerization rates between α- and β-xylopyranose in pathway optimization and sugar sensing is relatively unexplored.

Results

In this study, we tested the effect of expressing a xylose epimerase in S. cerevisiae strains carrying different xylose-consu

SUBMITTER: Persson VC 

PROVIDER: S-EPMC10629123 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature