The effect of anesthetic depth on postoperative delirium in older adults: a systematic review and meta-analysis.

ABSTRACT:

Background

Postoperative delirium (POD) is an important complication for older patients and recent randomised controlled trials have showed a conflicting result of the effect of deep and light anesthesia.

Methods

We included randomised controlled trials including older adults that evaluated the effect of anesthetic depth on postoperative delirium from PubMed, Embase, Web of Science and Cochrane Library. We considered deep anesthesia as observer's assessment of the alertness/ sedation scale (OAA/S) of 0-2 or targeted bispectral (BIS) < 45 and the light anesthesia was considered OAA/S 3-5 or targeted BIS > 50. The primary outcome was incidence of POD within 7 days after surgery. And the secondary outcomes were mortality and cognitive function 3 months or more after surgery. Th

SUBMITTER: Wang Y 

PROVIDER: S-EPMC10629190 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature