Polarization-Diversity Optical Coherence Tomography Assessment of Choroidal Nevi.

ABSTRACT:

Purpose

The purpose of this study was to demonstrate the utility of polarization-diversity optical coherence tomography (PD-OCT), a noninvasive imaging technique with melanin-specific contrast, in the quantitative and qualitative assessment of choroidal nevi.

Methods

Nevi were imaged with a custom-built 55-degree field-of-view (FOV) 400 kHz PD-OCT system. Imaging features on PD-OCT were compared to those on fundus photography, auto-fluorescence, ultrasound, and non-PD-OCT images. Lesions were manually segmented for size measurement and metrics for objective assessment of melanin distributions were calculated, including degree of polarization uniformity (DOPU), attenuation coefficient, and melanin occupancy rate (MOR).

Results

We imaged 17 patients (mean age = 69.5 yea

SUBMITTER: Miao Y 

PROVIDER: S-EPMC10629548 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature