Dynamic changes of left atrial substrate over time following pulmonary vein isolation: The Progress-AF study.

ABSTRACT:

Background

Little is known about dynamic changes of the left atrial (LA) substrate over time in patients with atrial fibrillation (AF).

Aim

To evaluate substrate changes following pulmonary vein isolation (PVI).

Methods

In our prospective observational study, consecutive patients undergoing first PVI-only and redo ablation were included. High-density maps of the two procedures were compared. Progression or Regression was diagnosed if significant concordant decrease or increase in bipolar voltages in ≥2 segments was observed, respectively.

Results

In 28 patients (61.2 ± 9.5 years, 39% female, 53.5% persistent AF), 111.013 voltage points from 56 high-density left atrial maps (1.982 points/patient) were analyzed. Comparing the high-density maps of the first and se

SUBMITTER: Marcon L 

PROVIDER: S-EPMC10629715 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature