Predicting hepatic encephalopathy in patients with cirrhosis: A UK population-based study and validation of risk scores.

ABSTRACT:

Background

HE is a common neurologic complication in cirrhosis associated with substantial disease and economic burden. HE symptoms are nonspecific and there are limited ways of identifying patients with cirrhosis at high risk of later developing HE. A risk score was previously developed to identify patients at risk of developing HE in a predominately male US cohort. Here, we evaluated the performance of the HE risk scores in a UK cohort study.

Methods

Health care records from Clinical Practice Research Datalink and linked Hospital Episode Statistics were used to select patients with cirrhosis who were diagnosed with HE, confirmed by a diagnosis code for HE or a rifaximin-α prescription. The index date was the date of incident cirrhosis. The study period was from January 200

SUBMITTER: Jones BI 

PROVIDER: S-EPMC10629733 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature