Quantitative interstitial lung disease scores in idiopathic inflammatory myopathies: longitudinal changes and clinical implications.

ABSTRACT:

Objectives

To investigate computer-aided quantitative scores from high-resolution CT (HRCT) images and determine their longitudinal changes and clinical significance in patients with idiopathic inflammatory myopathies (IIMs)-related interstitial lung disease (IIMs-ILD).

Methods

The clinical data and HRCT images of 80 patients with IIMs who underwent serial HRCT scans at least twice were retrospectively analysed. Quantitative ILD (QILD) scores (%) were calculated as the sum of the extent of lung fibrosis, ground-glass opacity, and honeycombing. The individual time-estimated ΔQILD between two consecutive scans was derived using a linear approximation of yearly changes.

Results

The baseline median QILD (interquartile range) scores in the whole lung were 28.1% (19.1-43.8)

SUBMITTER: Yeo J 

PROVIDER: S-EPMC10629794 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature