Relapse of Lung Adenocarcinoma Manifested by Spontaneous Tumor Lysis Syndrome.

ABSTRACT:

Introduction

Tumor lysis syndrome (TLS) is an oncologic emergency characterized by several metabolic derangements, such as hyperuricemia, hyperkalemia, hyperphosphatemia, and hypocalcemia. TLS is typically observed in hematologic malignancies, especially after starting the first administration of antineoplastic therapies. TLS in a solid malignancy is very unusual, and exceedingly rare when occurring spontaneously, in the absence of chemotherapy.

Case presentation

We report a case of a 76-year-old man with lung adenocarcinoma, which started as a cancer with indolent behavior and small tumor burden but relapsed in 5 months with rapidly proliferating metastatic disease. Spontaneous TLS was the presenting clinical manifestation of the tumor relapse, and it led to the patient's d

SUBMITTER: Im D 

PROVIDER: S-EPMC10629853 | biostudies-literature | 2023 Jan-Dec

REPOSITORIES: biostudies-literature