Being overweight worsens the relationship between urinary sodium excretion and albuminuria: the Wakuya study.

ABSTRACT:

Background/objectives

(Micro)albuminuria (a manifestation of renal microvascular damage) is an independent predictor of mortality risk, even when the urinary albumin/creatinine ratio is ≥ 10 mg/g in the general population. Excessive sodium intake and obesity are strong predictors of cardiovascular disease. However, the effect of obesity on the relationship between sodium intake and albuminuria is not fully understood.

Subjects/methods

The purpose of the present study was to investigate the cross-sectional relationships among dietary sodium intake, obesity, and albuminuria in a general population cohort. Subjects were 928 apparently healthy adults. Body mass index was calculated using the height and body weight. Urinary sodium/creatinine and albumin/creatinine ratios were mea

SUBMITTER: Tagawa K 

PROVIDER: S-EPMC10630129 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature