Alveolar cleft reconstruction using bone marrow aspirate concentrate and iliac cancellous bone: A 12-month randomized clinical study.

ABSTRACT:

Objective

This study aimed to compare the bone density and volume in patients with alveolar cleft reconstructions utilizing bone marrow aspirate concentrate with iliac graft versus iliac graft alone.

Material and methods

Thirty-six patients with unilateral alveolar cleft were randomly allocated into either an intervention group receiving an iliac bone graft mixed with bone marrow concentrate or a control group receiving an iliac bone graft. Cone beam CT was obtained preoperative, 6 and 12 months postoperatively to assess the bone density of the graft and bone volume of the alveolar defect, and then, the bone loss ratio was calculated.

Results

Bone volume and bone density demonstrated a statistically significant increase in the intervention group at 6 and 12 months. In

SUBMITTER: Shabaan AA 

PROVIDER: S-EPMC10630224 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature