Supportive care and antiviral treatments in primary herpetic gingivostomatitis: a systematic review.

ABSTRACT:

Objectives

Herpes simplex virus 1 (HSV-1) is the main pathogen responsible for herpes infections. In 13-30% of the cases, primary HSV-1 leads to the primary herpetic gingivostomatitis (PHGS), often a self-limiting infection; however, it can limit the ability to drink/eat with, sometimes, the need for hospitalization. Multiple therapeutic methods have been proposed. This systematic review aims to collect and critically appraise the available evidence about the clinical management of PHGS.

Materials and methods

Literature search including three databases (PubMed, Scopus, Embase), study design, and data analysis were performed following PRISMA guidelines, according to the PICO tool (PROSPERO n° CRD42023391386). Risk of bias was assessed with RoB 2 and ROBINS-I.

Results

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SUBMITTER: Coppola N 

PROVIDER: S-EPMC10630243 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature