DGAT inhibition at the post-absorptive phase reduces plasma FA by increasing FA oxidation.

ABSTRACT: In this Correspondence, A. Sharma & C. Wolfrum report that DGAT1/2 pharmacological inhibition at post-absorptive phase in mice leads to increased fatty acid oxidation and reduced plasma fatty acid levels, which could open new therapeutic avenues to avoid GI complications observed in clinical trials.

SUBMITTER: Sharma AK 

PROVIDER: S-EPMC10630880 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature