Pharmacotherapy for Alcohol Use Disorder: A Systematic Review and Meta-Analysis.

ABSTRACT:

Importance

Alcohol use disorder affects more than 28.3 million people in the United States and is associated with increased rates of morbidity and mortality.

Objective

To compare efficacy and comparative efficacy of therapies for alcohol use disorder.

Data sources

PubMed, the Cochrane Library, the Cochrane Central Trials Registry, PsycINFO, CINAHL, and EMBASE were searched from November 2012 to September 9, 2022 Literature was subsequently systematically monitored to identify relevant articles up to August 14, 2023, and the PubMed search was updated on August 14, 2023.

Study selection

For efficacy outcomes, randomized clinical trials of at least 12 weeks' duration were included. For adverse effects, randomized clinical trials and prospective cohort studies that

SUBMITTER: McPheeters M 

PROVIDER: S-EPMC10630900 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature