Development and validation of the CAIL prognostic score in non-small cell lung cancer patients with malignant pleural effusion.

ABSTRACT:

Background

Patients with malignant pleural effusion (MPE) typically have poor prognoses, and predicting survival is challenging. The present study aimed to identify prognostic factors of overall survival (OS) in non-small cell lung cancer (NSCLC) patients with MPE in the time of immunotherapy and targeted therapy.

Methods

Data of 344 consecutive NSCLC patients with MPE on clinical, radiological, and molecular characteristics and treatment options were collected. The risk factors in the training cohort were assessed using univariate and multivariate proportional hazards analyses. A clinical prognostic score was established and validated.

Results

According to the results of the multivariable survival analysis, the Eastern Cooperative Oncology Group (ECOG) performance sc

SUBMITTER: Li T 

PROVIDER: S-EPMC10632079 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature