Unveiling the role of cerebellar alterations in the autonomic nervous system: a systematic review of autonomic dysfunction in spinocerebellar ataxias.

ABSTRACT:

Background

Autonomic dysfunctions are prevalent in several cerebellar disorders, but they have not been systematically investigated in spinocerebellar ataxias (SCAs). Studies investigating autonomic deficits in SCAs are fragmented, with each one focusing on different autonomic dysfunctions and different SCA subtypes.

Methods

Following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement, we conducted a systematic review of the literature to assess the presence of autonomic dysfunctions in various SCAs. PubMed served as the primary database, and the Rayyan web application was employed for study screening.

Results

We identified 46 articles investigating at least one autonomic function in patients with SCA. The results were analyzed a

SUBMITTER: Urbini N 

PROVIDER: S-EPMC10632228 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature